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Addnok: Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

What is Buprenorphine ?

Buprenorphine is an opioid used to treat opioid use disorder, acute pain, and chronic pain. It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant. For opioid use disorder, it is typically started when withdrawal symptoms have begun and for the first two days of treatment under direct observation of a healthcare provider. The combination formulation of buprenorphine/naloxone (Suboxone) is recommended to discourage misuse by injection. Maximum pain relief is generally within an hour with effects up to 24 hours.

Addnok Products side effects:-

Side Effects of Addnok are Weakness, Anxiety, Nervousness, Dizziness, Drowsiness, Headache, Orthostatic hypotension (sudden lowering of blood pressure on standing), Constipation, Diarrhea, Nausea, Vomiting, Sweating.

Uses of Buprenorphine?

Buprenorphine is used to treat people with opioid use disorder. The combination formulation of buprenorphine/naloxone is generally preferred, like naloxone, an opioid antagonist has a higher bioavailability intravenously, and results in acute withdrawal if the formulation is crushed and injected, Prior to starting buprenorphine, individuals should wait long enough after their last dose of opioid until they have some withdrawal symptoms to allow for the medication to bind the receptors, but if taken too soon, buprenorphine can displace other opioids bound to the receptors and precipitate an acute withdrawal. The dose of buprenorphine is then adjusted until symptoms improve, and individuals remain on a maintenance dose through treatment.


Addnok Sublingual tablet is used to treat moderate to severe pain and drug dependence/addiction to opioids. It helps prevent withdrawal symptoms that may be caused due to withdrawal of other opioids.

Addnok Sublingual tablet should be taken in the dose and duration as advised by your doctor. Never take this medicine in greater amounts or more often than prescribed. It can be taken with or without food but should be taken at a fixed time. If you miss a dose take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Vomiting, dizziness, nausea, headache, difficulty sleeping and constipation are some of the common side effects that might be observed on taking this medicine. Some people may also experience anxiety, orthostatic hypotension (sudden decrease in blood pressure on standing) and diarrhea. Use caution while driving or using any machinery as it might cause drowsiness or visual disturbances.